高頻電燒刀於傳統臨床手術或微創手術中，扮演著不可或缺的角色。藉著手術切割時同步止血，不但可節省手術時間外，也能減少患者在手術中的失血。這樣的方式除了可降低傳統手術所造成的併發症外，其系統中高頻高壓的核心技術，在其他醫材應用也相當廣泛。本研究將設計一符合電燒刀規格之高頻高壓電源系統，其主要架構分為三個部分：主系統高壓電路、周邊輔助電路、周邊控制電路。主系統高壓電路以主動式功率因數修正電路(PFC)與後級隔離變壓器所組成，藉此產生穩定的前級電壓。周邊輔助電路與控制電路以脈衝寬度調變電路(PWM)與比例積分微分回授控制電路(PID)所組成，主要功能為提高電源輸出的穩定度。脈衝寬度調變電路為產生控制電源輸出所需要之時脈訊號，藉此達到有效輸出與快速散熱的目的；再經由推挽式放大電路做次級放大輸出。比例積分微分回授控制電路則用來偵測輸出負載的功率數值，使脈衝寬度調變電路能根據不同負載調整輸出工作週期。

High-frequency electrosurgery plays an important role in conservative surgical procedures and minimally invasive procedures. It is frequently used to stop bleeding instantly during surgical procedure. In addition, high-frequency electrosurgery can be used to save time, reduce blood loss and blood transfusion, and minimize the risk of complications which are caused by traditional scalpel. Hence, it is applied extensively in different types of surgery and in core technologies. The study designed ae high voltage power system of high frequency electrosurgery. The system could be divided into three parts: main system high-voltage circuit, peripheral auxiliary circuit, and peripheral control circuit. The main system high-voltage circuit which is composed of an active power factor correction circuit (PFC) and isolation transformer, produce constant primary voltage. The peripheral control circuit whose main function is to improve the stability of power output is composed of the pulse width modulation circuit (PWM) and the proportional-integral-derivative control feedback circuit (PID). The PWM is a clock signal to achieve the goal of effectiveness of power output and rapid heat dissipation; then via a push-pull amplifier circuit to generate a second amplifier output power. The PID is used to detect the value of output power and make the pulse width modulation circuit adjust the output duty cycle in accordance with different level of load.